QGC sets parameters, and when Pixhawk 2.4.8 is powered off and restarted, the parameters are reset again

hello,My PX4 firmware is version 1.15 v3. After speedometer calibration is added to the sensors and the system is restarted, it still needs to be calibrated.Is it because the PX4 firmware is incompatible with Pixhawk? Is Pixhawk 2.4.8 too old?