Preferred ESC Protocols for Pixracer and PX4

I have updated esc’s on my quad with DYS 40amp Opto BLHeli ESC’s (apparently loaded with OneShot125. Initial flight was very erratic and then an ESC fried. Is OneShot125 ok or should I downgrade it another protocol before trying again. Is there a preferred protocol for Pixracer and PX4.

First, try to run some test without Pixracer and then calibrate the ESCs with PX4 and then you can try again to go with it.